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GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Additionally we are shipping rho GTPase Activating Protein 44 Proteins (3) and many more products for this protein.
Showing 10 out of 27 products:
Human Polyclonal ARHGAP44 Primary Antibody for EIA, WB - ABIN492721
Richnau, Aspenström: Rich, a rho GTPase-activating protein domain-containing protein involved in signaling by Cdc42 and Rac1. in The Journal of biological chemistry 2001
Show all 5 references for ABIN492721
Human Polyclonal ARHGAP44 Primary Antibody for EIA, FACS - ABIN954549
Rollason, Korolchuk, Hamilton, Jepson, Banting: A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. in The Journal of cell biology 2009
Show all 2 references for ABIN954549
Besides the already known chromosome 6 associations, the analysis of low-frequency single nucleotide polymorphisms brought up a new association in the RICH2 gene for progression to AIDS.
Knocking down expression of RICH 2 causes loss of the apical actin network and apical microvilli, an increase in actin bundles at the basal surface, and a reduction in cell height. (RICH 2 protein)
Demonstrates that the (show ARHGAP1 Antibodies) RhoGAP domains of RICH-1 and RICH-2 can catalyze GT (show AK3 Antibodies)P hydrolysis of both Rac1 and Cdc4 (show CDC42 Antibodies)2, but not of Rho (show RHOA Antibodies)A.
RICH2 knockout animals display a selective and highly significant fear of novel objects and increased stereotypic behavior as well as impairment of motor learning.
These results suggested that Rich2 controls dendritic spine morphogenesis and function via inhibition of Rac1.
Knock-down of Rich2 or disruption of Rich2-Shank3 (show SHANK3 Antibodies) complex, inhibits dendritic spine enlargement.
Shows that the RhoGAP (show ARHGAP1 Antibodies) domain of the human RICH2 ortholog can catalyze GTP (show AK3 Antibodies) hydrolysis of both Rac1 and Cdc42 (show CDC42 Antibodies), but not of RhoA (show RHOA Antibodies).
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1.
Rho-type GTPase-activating protein RICH2
, Rho GTPase activating protein 44
, RhoGAP interacting with CIP4 homologs protein 2
, rho GTPase-activating protein 44
, rho GTPase-activating protein RICH2
, Rho GTPase-activating protein RICH2