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Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases (By similarity)..
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Human Polyclonal ARHGEF17 Primary Antibody for IHC, ELISA - ABIN1003259
Rümenapp, Freichel-Blomquist, Wittinghofer, Jakobs, Wieland: A mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domain. in The Biochemical journal 2002
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Interaction of the central domain of ARHGEF17 with Mps1 (show IDUA Antibodies).
The rho guanine nucleotide exchange factor 17 is drastically alter the effect of cGMP/cGK (show PRKG1 Antibodies) involving signaling pathways on RhoA (show RHOA Antibodies)-activated downstream effectors.
TEM4 contains a novel actin binding domain and binding to actin is essential for TEM4 subcellular localization and activity.
a Rho-specific GEF (show SLC2A4RG Antibodies) with novel structural and regulatory properties and predominant expression in the heart
Identification of ARHGEF17, mutations in melanoma.
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPases (By similarity).
164 kDa Rho-specific guanine-nucleotide exchange factor
, Rho-specific guanine-nucleotide exchange factor 164 kDa
, rho guanine nucleotide exchange factor 17
, tumor endothelial marker 4