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serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1) ELISA Kits

The protein encoded by SPINT1 is a member of the Kunitz family of serine protease inhibitors. Additionally we are shipping serine Peptidase Inhibitor, Kunitz Type 1 Antibodies (78) and serine Peptidase Inhibitor, Kunitz Type 1 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SPINT1 6692 O43278
Anti-Rat SPINT1 SPINT1 311331  
SPINT1 20732 Q9R097
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Top serine Peptidase Inhibitor, Kunitz Type 1 ELISA Kits at antibodies-online.com

Showing 2 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 0.039 ng/ml 0.156-10 ng/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details
Mouse 7.81pg/ml 31.25-2000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for serine Peptidase Inhibitor, Kunitz Type 1 Interaction Partners

Human serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1) interaction partners

  1. The findings suggest that the oncogenic activity of hepsin (show HPN ELISA Kits) arises not only from elevated expression level but also from depletion of HAI-1, events which together trigger gain-of-function activity impacting HGF (show HGF ELISA Kits)/MET signalling and epithelial cohesion

  2. HAI-1 may have a critical role in maintaining normal keratinocyte morphology through regulation of PAR-2 (show F2RL1 ELISA Kits)-dependent p38 mitogen-activated protein kinase (show MAPK14 ELISA Kits) signaling.

  3. the anti-migratory effects seen via gamma-catenin were driven by the expression of hepatocyte growth factor activator inhibitor Type I (HAI-1 or SPINT-1), an upstream inhibitor of the c-MET signaling pathway.

  4. Data suggest HAI1 exhibits structural features consistent with classification in MANEC subclass of PAN/apple domain family with unifying features such as two additional disulfide bonds, two extended loop regions, and additional alpha-helical elements.

  5. Matriptase (show ST14 ELISA Kits) activity was suppressed by the expression of HAI-1.

  6. The results of the present study identified HAI-1 as a favorable prognostic marker for prostate cancer and may indicate that HAI-1 could be a therapeutic target for the treatment of this malignancy.

  7. HAI-1 expression correlates with the differentiation status of colorectal epithelia and could serve as a differentiation marker.

  8. HAI-1 and HAI-2 influence proliferation and cell fate of NPCs and their expression levels are linked to BMP sign

  9. Crystal structures of matriptase (show ST14 ELISA Kits) in complex with its inhibitor hepatocyte growth factor activator inhibitor-1

  10. It is suggested that HAI-1 may play an important role in the pathogenesis of castration-resistant prostate cancer

Mouse (Murine) serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1) interaction partners

  1. HAI-1 may have a critical role in maintaining normal keratinocyte morphology through regulation of PAR-2 (show F2RL1 ELISA Kits)-dependent p38 mitogen-activated protein kinase (show MAPK14 ELISA Kits) signaling.

  2. HAI-1 regulates the activity of activated matriptase (show ST14 ELISA Kits), whereas HAI-2 (show SPINT2 ELISA Kits) has an essential role in regulating prostasin (show PRSS8 ELISA Kits)-dependent matriptase (show ST14 ELISA Kits) zymogen activation.

  3. HAI-1 and HAI-2 influence proliferation and cell fate of NPCs and their expression levels are linked to BMP sign

  4. HAI-1/SPINT1 has a crucial role in suppressing intestinal tumorigenesis, which implies a novel link between epithelial cell surface (show EPCAM ELISA Kits) serine protease (show F2 ELISA Kits) inhibitors and protection from carcinogenic stimuli.

  5. mutations in Prss8 (show PRSS8 ELISA Kits) restored placentation and normal development of HAI-1-deficient embryos and prevented early embryonic lethality, mid-gestation lethality due to placental labyrinth failure, and neural tube defects in HAI-2 (show SPINT2 ELISA Kits)-deficient embryos.

  6. HAI-1 has a crucial suppressive role in oral squamous cell carcinoma cells' invasiveness.

  7. HAI-1 and -2 are overexpressed in the liver in cholangiopathies with ductular reactions and are possibly involved in liver fibrosis and hepatic differentiation.

  8. HAI-1/SPINT1 plays an important role in maintaining colonic epithelium integrity.

  9. HAI-1 is required for branching morphogenesis in the chorioallantoic placenta.

  10. Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth.

serine Peptidase Inhibitor, Kunitz Type 1 (SPINT1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.

Gene names and symbols associated with SPINT1

  • serine peptidase inhibitor, Kunitz type 1 (SPINT1) antibody
  • serine peptidase inhibitor, Kunitz type 1 (Spint1) antibody
  • serine protease inhibitor, Kunitz type 1 (Spint1) antibody
  • HAI antibody
  • HAI-1 antibody
  • HAI1 antibody
  • MANSC2 antibody

Protein level used designations for SPINT1

serine peptidase inhibitor, Kunitz type 1 , kunitz-type protease inhibitor 1 , kunitz-type protease inhibitor 1-like , HAI-1 , hepatocyte growth factor activator inhibitor type 1 , serine protease inhibitor, Kunitz type 1 , hepatocyte growth factor activator inhibitor 1 , hepatocyte growth factor activator inhibitor-1

GENE ID SPECIES
423206 Gallus gallus
487501 Canis lupus familiaris
534040 Bos taurus
704578 Macaca mulatta
100157387 Sus scrofa
100345098 Oryctolagus cuniculus
100473505 Ailuropoda melanoleuca
100585940 Nomascus leucogenys
6692 Homo sapiens
311331 Rattus norvegicus
20732 Mus musculus
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