serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 Proteins (SERPINA1)

The protein encoded by SERPINA1 is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Additionally we are shipping SERPINA1 Antibodies (435) and SERPINA1 Kits (56) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SERPINA1 5265 P01009
SERPINA1 24648 P17475
SERPINA1    
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Top SERPINA1 Proteins at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Human Cells Human His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
HEK-293 Cells Human His tag 10 μg Log in to see 2 to 3 Days
$235.00
Details
HEK-293 Cells Human His tag Human Serpin A1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Log in to see 11 Days
$308.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$548.63
Details
Human Human Un-conjugated 1 mg Log in to see 2 to 3 Days
$85.00
Details
Escherichia coli (E. coli) Human His tag Validation with Western Blot 50 μg Log in to see 10 to 12 Days
$229.85
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Human Human His tag   10 μg Log in to see 15 to 16 Days
$300.00
Details

SERPINA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
, , , ,
Rat (Rattus) , ,

Mouse (Murine)

Top referenced SERPINA1 Proteins

  1. Human SERPINA1 Protein expressed in HEK-293 Cells - ABIN2714593 : Yao, Guihard, Blazquez-Medela, Guo, Moon, Jumabay, Boström, Yao: Serine Protease Activation Essential for Endothelial-Mesenchymal Transition in Vascular Calcification. in Circulation research 2015 (PubMed)

More Proteins for serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) Interaction Partners

Horse (Equine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. Although circulating nucleosomes and elastase - alpha 1-antitrypsin complexes are at present the best characterized biomarkers for neutrophil extracellular traps formation and neutrophil activation, their lack of association with rs2288904 genotype does not exclude a role for SLC44A2 (show SLC44A2 Proteins) in neutrophil activation (and possibly NET formation) in Venous Thromboembolism.

Chimpanzee serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. The mechanism underlying the alpha(1)PI deficiency that attends HIV-1 infection, was investigated.

Mouse (Murine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. Loss of alpha 1-Antitrypsin is associated with emphysema.

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. this study proved that SYVN1 (show SYVN1 Proteins) enhances SERPINA1(E342K)/ATZ degradation through SQSTM1 (show SQSTM1 Proteins)-dependent autophagy and attenuates SERPINA1(E342K)/ATZ cytotoxicity.

  2. Recombinant human alpha-1 antitrypsin-Fc fusion protein reduces acute myocardial inflammatory injury after ischemia-reperfusion in the mouse leading to preservation of viable myocardium and systolic function.

  3. report association of APOE (show APOE Proteins) and TOMM40 (show TOMM40 Proteins) with behavioural variant frontotemporal dementia, and ARHGAP35 (show GRLF1 Proteins) and SERPINA1 with progressive non-fluent aphasia.

  4. Our results indicated a high prevalence of SERPINA1 alleles in the normal Saudi population and an association between alpha-1 antitrypsin deficiency and COPD (show ARCN1 Proteins) development.

  5. findings highlight A1AT as a potential serum scavenger of hemin and suggest that the commercial preparations of human plasma A1AT might prove to be useful therapeutics in conditions associated with hemolysis.

  6. Reduced alpha-1-antitrypsin and elevated IL-23 (show IL23A Proteins) csf (show CSF2 Proteins) levels were seen in amyotrophic lateral sclerosis patients.

  7. the results of this study demonstrate a previously unknown role for P2 residue in determining inhibitory specificity of A1AT.

  8. high A1AT expression correlated with increased tumor stage, elevated p53 (show TP53 Proteins) staining and shorter overall survival in lung adenocarcinoma patients.

  9. These results clearly demonstrate that the association of malectin with ribophorin I is required to capture misfolded alpha1-antitrypsin and direct them to the degradation pathway.

  10. AAT (show SERPINA1A Proteins) heterozygous status in rheumatoid arthritis is strongly associated with positive anti-citrullinated peptide autoantibodies and may define a distinct subset of patients with increased disease severity.

Cow (Bovine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1) interaction partners

  1. Comparisons of the expression patterns of cattle fetuses and their dams show that the PI gene is biallelically expressed in fetuses and predominantly monoallelically expressed in the dams.

SERPINA1 Protein Profile

Protein Summary

The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with SERPINA1

  • serpin family A member 1 (SERPINA1)
  • serpin family A member 1 (Serpina1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 S homeolog (serpina1.S)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SPIA1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (serpina1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (Serpina1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog (serpina1.L)
  • A1A protein
  • A1AT protein
  • AAT protein
  • alpha-1-PI protein
  • alpha1AT protein
  • MGC64429 protein
  • Pi protein
  • PI1 protein
  • PRO2275 protein
  • SERPINA1 protein
  • serpina1d protein
  • Spi1 protein

Protein level used designations for SERPINA1

alpha-1 protease inhibitor , alpha-1-antiproteinase , alpha-1-antitrypsin , serpin A1 , alpha-1 antitrypsin , alpha-1-proteinase inhibitor , protease inhibitor 1 , serine (or cysteine) proteinase inhibitor, clade A (alpha-1antiproteinase, antitrypsin), member 1 , alpha-1-antitrypsin null , protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin , serine (or cysteine) proteinase inhibitor, clade A, member 1 , alpha-1-antitrypsin (protease inhibitor) , alpha-1-protease inhibitor , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 , serine protease inhibitor alpha 1 , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 , serine (or cysteine) proteinase inhibitor, clade A, member 1d , protease inhibitor 1 (anti-elastase, antitrypsin, alpha-1) , serine proteinase inhibitor, clade A, member 1 , alpha 1 antitrypsin , Alpha-1 protease inhibitor , serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 L homeolog

GENE ID SPECIES
100171544 Pongo abelii
443388 Ovis aries
5265 Homo sapiens
24648 Rattus norvegicus
379963 Xenopus laevis
397688 Sus scrofa
423434 Gallus gallus
467541 Pan troglodytes
701361 Macaca mulatta
100145012 Xenopus (Silurana) tropicalis
280699 Bos taurus
480422 Canis lupus familiaris
101841330 Mesocricetus auratus
397792 Xenopus laevis
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