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tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase Proteins (TRMU)

TRMU is a member of the trmU family. Additionally we are shipping tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase Antibodies (32) and tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRMU 55687 O75648
TRMU 72026 Q9DAT5
TRMU 362976  
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Top tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$3,157.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,234.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TRMU Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase (TRMU) Interaction Partners

Human tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase (TRMU) interaction partners

  1. Results show that post-transcriptional expression of GTPBP3 (show GTPBP3 Proteins), MTO1 and TRMU genes is down-regulated, leading to mt-tRNA hypomodification and contributing to mitochondrial dysfunction in MELAS cybrids.

  2. An additional, heterozygous mutation was detected in TRMU/MTU1. Although subject myoblasts and myotubes contained half the normal levels of TRMU, thiolation of mitochondrial tRNAs was normal.

  3. MTU1 is not required for mitochondrial translation.

  4. identification and characterization of a tRNA-modifying enzyme MTU1 (mitochondrial tRNA-specific 2-thiouridylase 1) that is responsible for the 2-thiolation of the wobble position in human and yeast mt tRNAs

  5. MTO2 may act as a modifier gene, modulating the phenotypic expression of the deafness-associated A1491G or C1409T mutation in mitochondrial 12 S rRNA

  6. These observations suggest that human TRMU may modulate the phenotypic manifestation of the deafness-associated mitochondrial 12S rRNA mutations.

  7. The mutated TRMU, related to transfer RNA modification, acting as a modifier factor modulates the phenotypic manifestation of deafness-associated 12S rRNA mutations.

  8. TRMU G28T single nucleotide polymorphism is present in 1 of the studied families for neurosensory nonsyndromic deafness

  9. There is a window of time whereby patients with TRMU mutations are at increased risk of developing liver failure.

Mouse (Murine) tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase (TRMU) interaction partners

tRNA 5-Methylaminomethyl-2-Thiouridylate Methyltransferase (TRMU) Protein Profile

Protein Summary

This gene is a member of the trmU family. It encodes a mitochondria-specific tRNA-modifying enzyme that is required for the 2-thio modification of 5-taurinomethyl-2-thiouridine tRNA-Lys on the wobble position of the anticodon.

Gene names and symbols associated with TRMU

  • tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase (TRMU)
  • tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase (Trmu)
  • tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase (trmu)
  • 1110005N20Rik protein
  • 1600025P05Rik protein
  • AI314320 protein
  • MTO2 protein
  • MTU1 protein
  • TRMT protein
  • Trmt1 protein
  • TRNT1 protein
  • zgc:110555 protein

Protein level used designations for TRMU

MTO2 homolog , mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase , mitochondrial tRNA-specific 2-thiouridylase 1 , tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1

GENE ID SPECIES
55687 Homo sapiens
481204 Canis lupus familiaris
616451 Bos taurus
72026 Mus musculus
362976 Rattus norvegicus
425909 Gallus gallus
553625 Danio rerio
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