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tRNA Aspartic Acid Methyltransferase 1 Proteins (TRDMT1)

TRDMT1 encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. Additionally we are shipping tRNA Aspartic Acid Methyltransferase 1 Antibodies (139) and tRNA Aspartic Acid Methyltransferase 1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRDMT1 1787 O14717
TRDMT1 13434 O55055
TRDMT1 291324 Q4G073
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Top tRNA Aspartic Acid Methyltransferase 1 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human GST tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,080.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,080.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$498.21
Details

TRDMT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced tRNA Aspartic Acid Methyltransferase 1 Proteins

  1. Human TRDMT1 Protein expressed in Escherichia coli (E. coli) - ABIN1098605 : Franchina, Hooper, Kay: Five novel alternatively spliced transcripts of DNA (cytosine-5) methyltransferase 2 in human peripheral blood leukocytes. in The international journal of biochemistry & cell biology 2001 (PubMed)
    Show all 2 references for ABIN1098605

  2. Human TRDMT1 Protein expressed in Baculovirus infected Insect Cells - ABIN2004124 : Dong, Yoder, Zhang, Zhou, Bestor, Cheng: Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA. in Nucleic acids research 2001 (PubMed)

More Proteins for tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) Interaction Partners

Human tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) interaction partners

  1. The strong effect of some of the somatic cancer mutations on DNMT2 activity suggests that these mutations have a functional role in tumorigenesis.

  2. DNMT1 (show DNMT1 Proteins), DNMT2 and DNMT3A (show DNMT3A Proteins) may play important roles in gastric cancer carcinogenesis.

  3. Mapped is the tRNA binding site of DNMT2 by systematically mutating surface-exposed lysine and arginine residues to alanine and studying the tRNA methylation activity and binding of the corresponding variants.

  4. the role of Dnmt2 in stress granules could represent a primitive cellular defense mechanism against viral infection.

  5. The expression of DNMT1 (show DNMT1 Proteins), DNMT2, DNMT3A (show DNMT3A Proteins) and DNMT3B (show DNMT3B Proteins) in pediatric acute lymphoblastic leukemia patients, was investigated.

  6. Hepatitis B virus-induced overexpression of DNMTs leads to viral DNA methylation (show HELLS Proteins) and decreased viral gene expression and also leads to methylation of host CpG islands.

  7. cDNA microarray analysis identified several genes involved in DNA methylation (show HELLS Proteins), such as DNMT2 and DNMT3a (show DNMT3A Proteins) that were more highly expressed in LNCaP-r (an androgen sensitive prostate cancer cell line).

  8. genetic and biochemical approach revealed that DNMT2 did not methylate DNA but instead methylated aspartic acid transfer RNA (tRNA(Asp (show ASIP Proteins))) and that DNMT2 specifically methylated cytosine 38 in the anticodon loop

  9. An association study of 45 folate-related genes in spina bifida: Involvement of tRNA aspartic acid methyltransferase 1 (TRDMT1)

Mouse (Murine) tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) interaction partners

  1. Dnmt2 plays an important role in haematopoiesis and define a novel function of C38 (show CEND1 Proteins) tRNA methylation in the discrimination of near-cognate codons, thereby ensuring accurate polypeptide synthesis.

  2. these findings uncover a novel function of Dnmt2 in RNA-mediated epigenetic heredity

  3. Dnmt2-dependent methylomes lack defined DNA methylation (show HELLS Proteins) patterns.

  4. Steady-state levels of unmethylated tRNAs were substantially reduced, and loss of Dnmt2 and NSun2 (show NSUN2 Proteins) was further associated with reduced rates of overall protein synthesis.

  5. the role of Dnmt2 in stress granules could represent a primitive cellular defense mechanism against viral infection.

tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) Protein Profile

Protein Summary

This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.

Gene names and symbols associated with TRDMT1

  • tRNA aspartic acid methyltransferase 1 (trdmt1)
  • tRNA aspartic acid methyltransferase 1 (LOC100230580)
  • tRNA aspartic acid methyltransferase 1 (TRDMT1)
  • tRNA aspartic acid methyltransferase 1 (Trdmt1)
  • DMNT2 protein
  • dnmt2 protein
  • MGC89267 protein
  • MHSAIIP protein
  • PUMET protein
  • RNMT1 protein
  • Rnmt2 protein

Protein level used designations for TRDMT1

tRNA aspartic acid methyltransferase 1 , DNA (cytosine-5)-methyltransferase-like protein 2 , DNA MTase homolog HsaIIP , DNA methyltransferase-2 , tRNA (cytosine(38)-C(5))-methyltransferase , tRNA (cytosine-5-)-methyltransferase , DNA MTase homolog MmuIIP , DNA methyltransferase 2 , DNA methyltransferase homolog MmuIIP , m.MmuIIP , met-2 , DNA (cytosine-5-)-methyltransferase 2

GENE ID SPECIES
448379 Xenopus (Silurana) tropicalis
100230580 Taeniopygia guttata
100346643 Oryctolagus cuniculus
100407322 Callithrix jacchus
100463906 Ailuropoda melanoleuca
100605724 Nomascus leucogenys
1787 Homo sapiens
13434 Mus musculus
379360 Xenopus laevis
420520 Gallus gallus
487116 Canis lupus familiaris
100302362 Sus scrofa
353353 Bos taurus
291324 Rattus norvegicus
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