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tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. Additionally we are shipping tRNA Methyltransferase 5 Homolog (S. Cerevisiae) Antibodies (14) and many more products for this protein.
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TRMT5 mutations cause a defect in post-transcriptional modification of mitochondrial tRNA associated with multiple respiratory-chain deficiencies.
Conservation of structure and mechanism by Trm5 enzymes
comparison of human TRM5 and E Coli TrmD activities, requirements for optimal activity, and tRNA methylation sites
tRNAs contain as many as 13 or 14 nucleotides that are modified posttranscriptionally by enzymes that are highly specific for particular nucleotides in the tRNA structure. TRMT5 methylates the N1 position of guanosine-37 (G37) in selected tRNAs using S-adenosyl methionine (Brule et al., 2004
TRM5 tRNA methyltransferase 5 homolog
, tRNA (guanine-N(1)-)-methyltransferase
, tRNA (guanine(37)-N1)-methyltransferase
, tRNA [GM37] methyltransferase
, tRNA methyltransferase 5 homolog
, tRNA-N1G37 methyltransferase