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THNSL2 encodes a threonine synthase-like protein. Additionally we are shipping threonine Synthase-Like 2 (S. Cerevisiae) Antibodies (30) and many more products for this protein.
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THNSL2 was found to have bimodal expression in human skeletal muscle tissue.
A cytokine named SOFAT (secreted osteoclastogenic factor of activated T cells) can induce osteoblastic IL-6 (show IL6 Proteins) production and osteoclast formation in the absence of osteoblasts or RANKL (show TNFSF11 Proteins). It is insensitive to RANKL (show TNFSF11 Proteins) inhibitor osteoprotegerin (show TNFRSF11B Proteins).
This gene encodes a threonine synthase-like protein. A similar enzyme in mouse can catalyze the degradation of O-phospho-homoserine to a-ketobutyrate, phosphate, and ammonia. This protein also has phospho-lyase activity on both gamma and beta phosphorylated substrates. In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts. Alternate splicing results in multiple transcript variants.
, threonine synthase-like 2
, secreted osteoclastogenic factor of activated T cells