Margatoxin

Catalog No. ABIN1540098

Product Details

Target: Margatoxin

Application: Blocking Reagent (BR)

Purpose: Margatoxin is a selective inhibitor of Kv1.3 channel

Sequence: Thr-Ile-Ile-Asn-Val-Lys-Cys7-Thr-Ser-Pro-Lys-Gln-Cys13-Leu-Pro-Pro-Cys17-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys29-Met-Asn-Gly-Lys-Cys34-Lys-Cys36-Tyr-Pro-His-OHDisulfid e bonds between Cys7-Cys29, Cys13-Cys34 and Cys17-Cys36

Application Details

Restrictions: For Research Use only

Handling

Target Details

Target: Margatoxin

Background: Margatoxin is a component of the venom of Scorpio Centruroides margaritatus. This toxin is a potent selective inhibitor of voltage-dependent potassium channels such as Kv1.3.

Molecular Weight: 4179.03 Da

CAS-No: 145808-47-5