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Interleukin 17F (IL17F) antibody (HRP)

Details for Product No. ABIN1043827, Supplier: Log in to see
Antigen
  • FISP
  • Mda7
  • St16
  • Mda-7
  • IL17F
  • IL-17F
  • CANDF6
  • ML-1
  • ML1
  • C87042
Reactivity
Mouse (Murine), Rat (Rattus)
145
44
19
Host
Rabbit
109
50
14
12
Clonality
Polyclonal
Conjugate
HRP
26
10
9
7
6
6
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
119
98
42
26
12
10
8
7
7
6
6
4
4
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Supplier
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Immunogen This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant mouse IL17-F protein.
Immunogen Type: Recombinant Protein
Isotype IgG
Specificity This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant mouse IL17-F in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
Characteristics IL17-F (also known as ML1, ML-1, IL17F, and IL24) is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angio-genesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/ GFB, and monocyte chemoattractant protein-1. IL-17F plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation.
Purification purified
Alternative Name IL-17F (IL17F Antibody Abstract)
Background IL17-F (also known as ML1, ML-1, IL17F, and IL24) is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angio-genesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/ GFB, and monocyte chemoattractant protein-1. IL-17F plays a role in the induction of neutrophilia in the lungs and in the exacerbation of antigen-induced pulmonary allergic inflammation.
Synonyms: IL-17F, Interleukin-17F, ML1, ML-1, IL17F, and IL24
Gene ID 257630
NCBI Accession NP_665855
UniProt Q7TNI7
Application Notes This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 17.9 kDa in size corresponding to mouse IL17-F protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
Comment

Gene Name: Il17f

Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
Concentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Preservative Gentamicin sulfate
Handling Advice Do NOT add Sodium Azide!
Storage 4 °C/-20 °C
Storage Comment Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
Expiry Date 12 months
Product cited in: Gomez-Rodriguez, Sahu, Handon et al.: "Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase." in: Immunity, Vol. 31, Issue 4, pp. 587-97, 2009 (PubMed).