SHROOM3 antibody

Catalog No. ABIN1077407

Product Details anti-SHROOM3 Antibody

Target: SHROOM3 (Shroom Family Member 3 (SHROOM3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHROOM3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: SHROOM3 antibody is human specific. At least four isoforms of SHROOM3 are known to exist, this antibody will detect all four isoforms. SHROOM3 antibody is predicted to not cross-react with other SHROOM family members.

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal SHROOM3 antibody was raised against an 18 amino acid peptide near the center of human SHROOM3.

Isotype: IgG

Application Details

Application Notes: SHROOM3 antibody can be used for detection of SHROOM3 by Western blot at 1 - 2 μg/mL.

Comment:

(IN) SHROOM family member 3

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C

Storage Comment: SHROOM3 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.

Expiry Date: 12 months

Target Details for SHROOM3

Target: SHROOM3 (Shroom Family Member 3 (SHROOM3))

Alternative Name: SHROOM3 (SHROOM3 Products)

Synonyms: APXL3 antibody, SHRM antibody, ShrmL antibody, AL022960 antibody, D5Ertd287e antibody, Shrm antibody, Shrm3 antibody, RGD1310470 antibody, apxl3 antibody, shrm antibody, shroom family member 3 antibody, shroom family member 3 L homeolog antibody, SHROOM3 antibody, shroom3 antibody, Shroom3 antibody, shroom3.L antibody

Background: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM3 is an actin-binding protein is a regulator of the microtubule cytoskeleton during epithelial morphogenesis and is sufficient and necessary to induce a redistribution of the microtubule regulator gamma-tubulin. It is necessary for both apiscobasal cell elongation and apical constriction in the neural epithelium. SHROOM3 has also been shown to be essential for cell shape changes and morphogenesis in the developing vertebrate gut, with its transcription relying on the Pitx1 transcription factor.
Synonyms: SHROOM family member 3, APXL3, SHRM, ShrmL, F-actin-binding

Molecular Weight: 220 kDa

Gene ID: 57619

NCBI Accession: NP_065910

Pathways: Tube Formation, Asymmetric Protein Localization