PIBF1 antibody (C-Term)

Catalog No. ABIN1077444

Product Details anti-PIBF1 Antibody

Target: PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIBF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Multiple isoforms of PIBF1 exists as a result of alternative splicing event.

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal PIBF1 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human PIBF1.

Isotype: IgG

Application Details

Application Notes: PIBF1 antibody can be used for detection of PIBF1 by Western blot at 1 - 2 μg/mL.

Comment:

(CT) Progesterone immunomodulatory binding factor 1

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Target Details for PIBF1

Target: PIBF1 (Progesterone Immunomodulatory Binding Factor 1 (PIBF1))

Alternative Name: PIBF1 (PIBF1 Products)

Synonyms: D14Ertd581e antibody, 1700017E21Rik antibody, 4930513H15Rik antibody, 4933438D16Rik antibody, 4933439E17Rik antibody, RGD1305077 antibody, PIBF antibody, C13orf24 antibody, zgc:101063 antibody, MGC80410 antibody, CEP90 antibody, RP11-505F3.1 antibody, progesterone immunomodulatory binding factor 1 antibody, progesterone immunomodulatory binding factor 1 S homeolog antibody, Pibf1 antibody, PIBF1 antibody, pibf1 antibody, pibf1.S antibody

Background: PIBF1 is synthesized during pregnancy in response to progesterone by T lymphocytes. PIBF1 inhibits arachidonic acid release, controls NK activity, and modifies the cytokine balance exerting an anti-abortive effect. It contains a leucine zipper motif, a basic zipper sequence, a PEST sequence, a nuclear localization signal, an ER membrane retention signal and N-glycosylation and phosphorylation sites. PIBF1 is significantly higher in healthy pregnant women than in women at risk for premature pregnancy termination. Full-length PIBF1 is associated with the nucleus and functions as a transcription factor, whereas secretion of shorter forms which may act as cytokines is induced by activation of the cell.
Synonyms: Progesterone immunomodulatory binding factor 1, Progesterone-induced-blocking factor 1, PIBF

Molecular Weight: 83 kDa

Gene ID: 10464

NCBI Accession: NP_006337