FPR2 antibody

Catalog No. ABIN108736

Product Details anti-FPR2 Antibody

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FPR2 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: GM1D6 recognises FPRL1 transiently expressed on the cell surface of transfected BOSC cells.

Purification: Protein G

Immunogen: genetic immunisation with cDNA encoding human FPRL1

Clone: GM-1D6

Isotype: IgG1

Application Details

Application Notes: Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Comment:

Synonyms: FPR2

Restrictions: For Research Use only

Handling

Concentration: 2mg/ml

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C

Storage Comment: short term: 2 °C - 8 °C, long term: -20 °C

References for anti-FPR2 antibody (ABIN108736)

Nadkarni, Cooper, Brancaleone, Bena, Perretti: "Activation of the Annexin A1 Pathway Underlies the Protective Effects Exerted by Estrogen in Polymorphonuclear Leukocytes." in: Arteriosclerosis, thrombosis, and vascular biology, (2011) (PubMed).

Target Details for FPR2

Target: FPR2 (Formyl Peptide Receptor 2 (FPR2))

Alternative Name: FPRL1 (FPR2 Products)

Synonyms: ALXR antibody, FMLP-R-II antibody, FMLPX antibody, FPR2A antibody, FPRH1 antibody, FPRH2 antibody, FPRL1 antibody, HM63 antibody, LXA4R antibody, E330010I07Rik antibody, Fpr-rs2 antibody, Fprl1 antibody, ALX antibody, Fpr-rs1 antibody, Fpr-s1 antibody, LXA4-R antibody, Lxa4r antibody, FMLP-R-I antibody, FPR2 antibody, formyl peptide receptor 2 antibody, formyl peptide receptor 3 antibody, N-formyl peptide receptor 2 antibody, FPR2 antibody, Fpr2 antibody, Fpr3 antibody, LOC100444626 antibody

Background: FPRL1 belongs to the large family of G-protein coupled receptors (GPCR). FPRL1 is expressed on neutrophils and it was shown that chemokines can be potent and specific ligands. Therefore, FPRL1 might have interesting functions in inflammatory pathways. GM1D6 was generated by genetic immunisation.

UniProt: P25090