RCAN3 Protein (His tag)
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- Target See all RCAN3 Proteins
- RCAN3 (RCAN Family Member 3 (RCAN3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RCAN3 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
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RCAN Family Member 3 (RCAN3) (AA 1-241) protein (GST tag)
RCAN3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
RCAN Family Member 3 (RCAN3) (AA 1-241) protein (Strep Tag)Crystallography grade RCAN3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
RCAN Family Member 3 (RCAN3) (AA 1-239) protein (Strep Tag)Crystallography grade RCAN3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
RCAN Family Member 3 (RCAN3) protein (Myc-DYKDDDDK Tag)RCAN3 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Comment
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Synonyms: Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 20% glycerol, 0.2 M NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- RCAN3 (RCAN Family Member 3 (RCAN3))
- Alternative Name
- RCAN3 (RCAN3 Products)
- Synonyms
- DSCR1L2 Protein, rcn3 Protein, hrcn3 Protein, mcip3 Protein, dscr1l2 Protein, MGC145788 Protein, MCIP3 Protein, RCN3 Protein, hRCN3 Protein, Dscr1l2 Protein, AU041093 Protein, Csp3 Protein, wu:fc68f05 Protein, zgc:113155 Protein, zgc:91820 Protein, RCAN family member 3 Protein, calcipressin-3 Protein, regulator of calcineurin 3 Protein, RCAN3 Protein, Tsp_08182 Protein, rcan3 Protein, Rcan3 Protein
- Background
- Calcipressin-3, also known as RCAN3, is a 241 amino acid protein that potentially is involved in central nervous system development. RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Overexpression of calcipressin-3 results in inhibition of calcineurin activity towards the nuclear factor of activated T-cells (NFAT) transcription factors and also downregulates NFAT-dependent cytokine gene expression in activated Jurkat T-cells. Highest expression occurs in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Recombinant human RCAN3 protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 23.5 kDa (209aa)
- NCBI Accession
- NP_038469
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