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Caldesmon antibody (Caldesmon 1)

Details for Product anti-CALD1 Antibody No. ABIN1105638, Supplier: Log in to see
Antigen
  • CALD1
  • caldesmon
  • si:bz30i22.4
  • si:rp71-30i22.4
  • zgc:56389
  • CDM
  • H-CAD
  • HCAD
  • L-CAD
  • LCAD
  • NAG22
  • 4833423D12Rik
  • AI195384
  • AV071549
  • AW536160
  • C920027I18Rik
  • l-Cad
  • caldesmon 1
  • B-cell receptor-associated protein 31
  • caldesmon-like
  • CALD1
  • bcap31
  • Cald1
  • LOC100546285
Alternatives
anti-Human Caldesmon antibody for Enzyme Immunoassay
Reactivity
Human
325
110
97
26
21
7
6
6
5
5
5
4
4
3
1
1
1
Host
Mouse
180
150
Clonality (Clone)
Monoclonal ()
Conjugate
This Caldesmon antibody is un-conjugated
11
9
9
9
9
7
7
7
7
7
7
7
7
7
7
7
7
6
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
170
138
137
88
69
51
29
26
18
13
6
5
3
3
1
1
1
Options
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Immunogen Caldesmon from turkey gizzard
Clone CD-7
Isotype IgG1
Specificity This antibody reacts to Caldesmon (smooth).
Purification Affinity chromatography
Alternative Name Caldesmon (CALD1 Antibody Abstract)
Background Caldesmon is a potential actomyosin regulatory protein found in smooth muscle and nonmuscle cells.The predicted smooth-muscle polypeptide is 793 amino acids long. The high molecular weight caldesmon (h-CaD) is predominantly expressed in smooth muscles, whereas the low molecular weight caldesmon (l-CaD) is widely distributed in nonmuscle tissues and cells. Hayashi et al. (1992) demonstrated that the human CDM gene is composed of 14 exons.Synonyms: CAD, CALD1, CDM
Gene ID 800
NCBI Accession NP_004333
UniProt Q05682
Research Area Cardiovascular, Contractility, Cytoskeleton, Microfilaments
Pathways Myometrial Relaxation and Contraction
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Reconstitution Restore with 1.2 % sodium acetate or neutral PBS
Concentration 0,1 mg/mL
Buffer 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Hayashi, Yano, Hashida, Takeuchi, Takeda, Asada, Takahashi, Kato, Sobue: "Genomic structure of the human caldesmon gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 24, pp. 12122-6, 1993 (PubMed).

Humphrey, Herrera-Sosa, Gonzalez, Lee, Bryan: "Cloning of cDNAs encoding human caldesmons." in: Gene, Vol. 112, Issue 2, pp. 197-204, 1992 (PubMed).