Perforin 1 antibody

Catalog No. ABIN110571

The Rabbit Polyclonal anti-Perforin 1 antibody (ABIN110571) specifically detects Perforin 1 in WB. The antibody is reactive with Rat samples.

Quick Overview for Perforin 1 antibody (ABIN110571)

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Perforin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Perforin 1 Antibody

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: 4 °C

Target Details for Perforin 1

Target: Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

Alternative Name: Perforin (Pore-Forming Protein)

Background: Perforin (pore-forming protein) is originally cloned from mouse cytotoxic T-lymphocyte (CTL)1, 2, . It is a 555-amino acid protein with a 21-amino acid signal peptide. Perforin is a cytolytic mediator produced by killer lymphocytes, and is stored in and released by cytoplasmic granules. Perforin is involved in the killing mediated by CTL which represents an important mechanism in the immune defense against tumors and virus infections 3, 4.

Pathways: Apoptosis, Caspase Cascade in Apoptosis