IKBa antibody
| Antigen |
|
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
|
|
Application
|
|
| Catalog no. |
ABIN110585 |
| Quantity |
0.2mg |
| Price |
325.00 $ Plus shipping costs $35.00
|
| Shipping to |
|
| Availability |
Ships within 3 to 5 Business Days |
|
Format
|
Protein A purified, 0.1% sodium azide, Lyophilized
|
|
Description
|
I.Ba protein is a NF-.B inhibitory protein. It binds NF-.B, retains the complex in the cytoplasma, prevents it from entering nuclear and functioning as a transcription factor. Upon receiving a variety of signals, I.Ba undergoes phosphorylation at serine residues by a ubiquitin-dependent protein kinases and finally degraded by the proteasome. Free NF-.B then binds to DNA and affects gene expression 1,2.
|
|
Storage
|
4°C for short term storage or -20°C in small aliquots for long term storage. Avoid repeated freeze and thaw. Reconstitute to 1 mg/ml by adding 200 µl PBS
|
|
Research Area
|
Transcription Factors
|
|
Restrictions
|
For Research Use only
|
Alternatives for antigen "IKBa", type "Antibodies"
Alternatives 
