C3AR1 antibody

Catalog No. ABIN110596

Product Details anti-C3AR1 Antibody

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C3AR1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Storage: 4 °C

Target Details for C3AR1

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Alternative Name: C3a Receptor (C3AR1 Products)

Synonyms: C3AR antibody, C3a-R antibody, c3ar1 antibody, AZ3B antibody, HNFAG09 antibody, C3a anaphylatoxin chemotactic receptor antibody, complement C3a receptor 1 antibody, complement component 3a receptor 1 antibody, c3ar1 antibody, C3AR1 antibody, C3ar1 antibody

Background: C3a is an anaphylatoxin generated through activation of the complement C3. C3a is a potent chemoattractant for phagocytes, and it stimulates chemotaxis and other leukocyte functions. C3a binds to eosinophils, basophils, neutrophils, and differentiated U937 cells, that all express receptors for C3a on their cell surface. The C3a receptor has been cloned and shown to be a G protein-coupled receptor with seven putative transmembrane domains1,2. This receptor is characterized for its large extracellular loop between the fourth and fifth transmembrane domains3. The loop can be readily detected using the rabbit anti-C3a receptor antibody.

Pathways: Complement System