C3AR1 antibody (PE)
Quick Overview for C3AR1 antibody (PE) (ABIN7505847)
Target
See all C3AR1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Hu C3aR PE
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Characteristics
- The mouse monoclonal antibody HC3aRZ8 recognizes an extracellular epitope of C3aR, a transmembrane chemotactic receptor for C3a anaphylatoxin.
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Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogen
- Human C3aR transfectants
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Isotype
- IgG2b
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Application Notes
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Do not freeze,Protect from prolonged exposure to light
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Storage
- 4 °C
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Storage Comment
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- C3AR1 (Complement Component 3a Receptor 1 (C3AR1))
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Alternative Name
- C3aR
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Background
- Complement C3a receptor 1,C3aR is a 7TM transmembrane protein associated with G proteins, and serves as a receptor for C3a complement fragment. It is expressed mainly on neutrophils, mast cells, basophils, eosinophils, dendritic cells, monocytes, and macrophages. Upon detection of its ligand, the activated C3aR signaling cascade results in degranulation, superoxide production, and chemotaxis.,AZ3B, HNFAG09
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Gene ID
- 719
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UniProt
- Q16581
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Pathways
- Complement System
Target
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