C3AR1 antibody

Catalog No. ABIN7505846

The Mouse Monoclonal anti-C3AR1 antibody (Clone HC3aRZ8) (ABIN7505846) specifically detects C3AR1 in FACS and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for C3AR1 antibody (ABIN7505846)

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C3AR1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: HC3aRZ8

Product Details anti-C3AR1 Antibody

Purpose: Anti-Hu C3aR Purified

Characteristics: The mouse monoclonal antibody HC3aRZ8 recognizes an extracellular epitope of C3aR, a transmembrane chemotactic receptor for C3a anaphylatoxin.

Purification: Purified by protein-A affinity chromatography.

Immunogen: Human C3aR transfectants

Isotype: IgG2b

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for C3AR1

Target: C3AR1 (Complement Component 3a Receptor 1 (C3AR1))

Alternative Name: C3aR

Background: Complement C3a receptor 1,C3aR is a 7TM transmembrane protein associated with G proteins, and serves as a receptor for C3a complement fragment. It is expressed mainly on neutrophils, mast cells, basophils, eosinophils, dendritic cells, monocytes, and macrophages. Upon detection of its ligand, the activated C3aR signaling cascade results in degranulation, superoxide production, and chemotaxis.,AZ3B, HNFAG09

Gene ID: 719

UniProt: Q16581

Pathways: Complement System