CCR3 antibody (Chemokine (C-C Motif) Receptor 3) (PE)

Details for Product anti-CCR3 Antibody No. ABIN1105991, Supplier: Log in to see
Antigen
  • CC-CKR-3
  • CD193
  • CKR3
  • CMKBR3
  • CC-CKR3
  • Cmkbr1l2
  • Cmkbr3
  • chemokine (C-C motif) receptor 3
  • CCR3
  • Ccr3
Reactivity
Human
260
102
45
5
1
Host
Mouse
125
99
84
10
Clonality (Clone)
Monoclonal ()
Conjugate
This CCR3 antibody is conjugated to PE
28
14
13
10
10
10
10
9
8
8
7
5
5
5
4
4
4
4
4
4
4
4
3
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
181
100
69
61
45
13
12
8
8
5
4
2
2
2
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Human CCR3 expressing transfectant (mouse pre B cell lymphoma B300-19)
Clone 444-11
Isotype IgG1
Specificity This antibody reacts with human CD193 antigen.
Purification Protein A agarose
Alternative Name CD193 / CCR3 (CCR3 Antibody Abstract)
Background Dendritic cells (DCs) are major antigen presenting cells (APCs) capable of stimulation resting T cells (TCs) in the primary immune response and are more potent APCs than peripheral blood monocytes or B cells. Several CC and CXC chemokines receptors were found to be expressed on some DCs and these molecules have been implicated to mediate in part the trafficking of DCs from blood to tissues and then to lymph nodes, where they form a close association with TCs in the process of antigen presentation. Recent studies have shown that CD191/CCR1 and CD193/CCR3 are potentially involved in antigen-presenting cell function of human DCs.Synonyms: C-C CKR-3, C-C chemokine receptor type 3, CC-CKR-3, CCR-3, CKR3, CMKBR3, Eosinophil eotaxin receptor
Gene ID 1232
NCBI Accession NP_001828
UniProt P51677
Research Area Chemokines, Receptors, CD Antigens
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer 50 tests in 1 mL volume of PBS, 0.09 % NaN3, 1 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 2 - 8 °C.
Supplier Images
Flow Cytometry (FACS) image for anti-Chemokine (C-C Motif) Receptor 3 (CCR3) antibody (PE) (ABIN1105991) anti-Chemokine (C-C Motif) Receptor 3 (CCR3) antibody (PE)
Background publications Fukagawa, Okada, Fujishima, Nakajima, Tsubota, Takano, Kawasaki, Saito, Hirai: "CC-chemokine receptor 3: a possible target in treatment of allergy-related corneal ulcer." in: Investigative ophthalmology & visual science, Vol. 43, Issue 1, pp. 58-62, 2002 (PubMed).

Nakayama, Fujisawa, Izawa, Hieshima, Takada, Yoshie: "Human B cells immortalized with Epstein-Barr virus upregulate CCR6 and CCR10 and downregulate CXCR4 and CXCR5." in: Journal of virology, Vol. 76, Issue 6, pp. 3072-7, 2002 (PubMed).

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