JIP3 antibody (N-Term)

Catalog No. ABIN1107892

Product Details anti-JIP3 Antibody

Target: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This JIP3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: MEIQMDEGGG VV-C

Cross-Reactivity (Details): Species reactivity (expected):Human, Rat, Bovine.
Species reactivity (tested):Mouse.

Purification: Affinity Chromatography

Immunogen: Peptide with sequence from the N Terminus of the protein sequence according to NP_055948.2, NP_001035529.1. Genename: MAPK8IP3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for JIP3

Target: JIP3 (MAPK8IP3) (Mitogen-Activated Protein Kinase 8 Interacting Protein 3 (MAPK8IP3))

Alternative Name: JIP-3 (MAPK8IP3 Products)

Synonyms: JIP3 antibody, JSAP1 antibody, SYD2 antibody, syd antibody, BB120594 antibody, D17Wsu15e antibody, JIP-3 antibody, JSAP1a antibody, JSAP1b antibody, JSAP1c antibody, JSAP1d antibody, Jip3 antibody, Syd2 antibody, mKIAA1066 antibody, mitogen-activated protein kinase 8 interacting protein 3 antibody, MAPK8IP3 antibody, mapk8ip3 antibody, Mapk8ip3 antibody

Background: MAPK8IP3 shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport.Synonyms: C-jun-amino-terminal kinase-interacting protein 3, JIP3, JNK MAP kinase scaffold protein 3, JNK-interacting protein 3, MAPK8IP3, Mitogen-activated protein kinase 8-interacting protein 3

Gene ID: 23162

NCBI Accession: NP_001035529