LY86 antibody (FITC)

Catalog No. ABIN1108081

Product Details anti-LY86 Antibody (FITC)

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This LY86 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Specificity: The monoclonal antibody MD113 reacts with mouse MD-1. The antibody is antagonistic in LPS-induced B-cell proliferation and B7.2 up-regulation.

Cross-Reactivity (Details): Species reactivity (tested):Mouse

Purification: Protein G

Clone: MD113

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 1.0 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for LY86

Target: LY86 (Lymphocyte Antigen 86 (LY86))

Alternative Name: LY86 / MD-1 (LY86 Products)

Synonyms: MD-1 antibody, MMD-1 antibody, dJ80N2.1 antibody, MD1 antibody, LY86 antibody, lymphocyte antigen 86 antibody, LY86 antibody, Ly86 antibody

Background: MD-1 (22-25 kD) is an extracellular protein associated with the extracellular domain of RP105. The latter is a type 1 transmembrane protein with leucine-rich repeats. RP105 is similar to Drosophila Toll. MD-1 associated with RP105 (similar to TLR4/MD-2) appears to be an essential molecule that helps RP105 on B-cells to signal to LPS.Synonyms: Lymphocyte antigen 86, MD1

Gene ID: 17084

Pathways: Toll-Like Receptors Cascades