Afadin antibody (AA 1814-1829)

Catalog No. ABIN1108256

The Mouse Monoclonal anti-Afadin antibody has been validated for WB, IP and EIA. It is suitable to detect Afadin in samples from Human, Rat, Mouse and Dog.

Quick Overview for Afadin antibody (AA 1814-1829) (ABIN1108256)

Target: Afadin (MLLT4)

Reactivity: Human, Rat, Mouse, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This Afadin antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: 3

Product Details anti-Afadin Antibody

Binding Specificity: AA 1814-1829

Specificity: This antibody detects L-Afadin.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat, dog

Purification: Protein G

Immunogen: Peptide 1814-1829 aa of rat l-afadin

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2 - 8 °C.

Target Details for Afadin

Target: Afadin (MLLT4)

Alternative Name: MLLT4 / AF6 / Afadin

Background: Afadin is an actin filament-binding protein that is involved in cell-cell adherens junctions (AJs) which directly interacts with the alpha herpus virus receptor, a member of the immunoglobulin supergene family. Afadin is colocalized with nectin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. L-Afadin has been isolated as an F-actin-binding protein from rat brain. L-afadin is ubiquitously expressed and specifically localized at zonula adherens (ZA) in epithelial cells and at cell-cell adherens junctions (AJs) in non-epithelial cells. L-afadin has a splice variant, named small intestine absorptive afadin (s-afadin) which is abundantly expressed in neural tissue.Synonyms: Myeloid/lymphoid Or Mixed-lineage Leukemia Translocated To 4, Protein AF-6

Gene ID: 26955

NCBI Accession: NP_037349

UniProt: O35889

Pathways: Cell-Cell Junction Organization