OPCML antibody (C-Term)

Catalog No. ABIN1108524

Product Details anti-OPCML Antibody

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPCML antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects OPCML / OBCAM (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Immunogen affinity purified

Immunogen: Synthetic peptide mapping at the C-terminal of human OPCML .Remarks: Peptide is identical to the related rat and mouse sequence.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3

Preservative: Sodium azide, Thimerosal (Merthiolate)

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Target Details for OPCML

Target: OPCML (Opioid Binding Protein/cell Adhesion Molecule-Like (OPCML))

Alternative Name: OPCML / OBCAM (OPCML Products)

Synonyms: IGLON1 antibody, OBCAM antibody, OPCM antibody, 2900075O15Rik antibody, 3732419F12 antibody, AI844366 antibody, B930023M13Rik antibody, C230027C17 antibody, Gm181 antibody, Obcam antibody, opioid binding protein/cell adhesion molecule like antibody, opioid binding protein/cell adhesion molecule-like antibody, OPCML antibody, Opcml antibody

Background: Opioid-binding protein/cell adhesion molecule-like (OPCML), (also called opioid-binding cell adhesion molecule (OBCAM)). OPCML is a member of the IgLON family of immunoglobulin (Ig)domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules, as an excellent candidate for the 11q25 ovarian cancer TSG in EOC. The OPCML gene comprises 7 exons,spans approximately 600 kb, and is transcribed from telomere to centromere . And due to the lack of transmembrane domains necessary for signal transduction, it is improbable that OBCAM acts independently as an opioid receptor, more likely, it plays an important accessory role in opioid receptor function.Synonyms: Opioid-binding cell adhesion molecule, Opioid-binding protein/cell adhesion molecule

Gene ID: 4978

NCBI Accession: NP_002536

UniProt: Q14982