The Rabbit Polyclonal anti-RBPJ antibody (ABIN1108842) specifically detects RBPJ in WB and IHC (p).
The antibody is reactive with Human, Mouse, Dog, Cow and Xenopus laevis samples.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Reconstitution
Add 50 μL of distilled water
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the lyophised antibody at -20 °C for up to one year. Store reconstitued antibody undiluted for one month or in aliquots at -20 °C long term.
Expiry Date
12 months
Target
RBPJ
(Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
Alternative Name
RBP-J kappa / RBPJ
Background
RBPSUH is a DNA binding protein that activates a full transcriptional response but only demonstrates partial anti-apoptotic activity. RTA-mediated redirection of RBPSUH activity from repression to activation is critical for lytic viral replication.Synonyms: IGKJRB, IGKJRB1, J kappa-recombination signal-binding protein, NY-REN-30, RBP-J, RBP-JK, RBPJK, RBPSUH, Recombining binding protein suppressor of hairless, Renal carcinoma antigen NY-REN-30