SCP2 antibody (Internal Region)

Catalog No. ABIN1108955

Product Details anti-SCP2 Antibody

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This SCP2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-KNHKHSVNNP YSQ Remarks: Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Orangutan (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Rat (100%), Hamster (100%), Elephant (100%), Bat (100%), Bovine (100%), Horse (100%), Rabbit (100%), Opossum (100%), Drosophila (100%), Ant (100%), Beetle (100%), M. tuberculos is (92%).

Specificity: This antibody is expected to recognize isoform 1, 2, 6, 7 and 8 of SCP2 (NP_002970.2, NP_001007099.1, NP_001180529.1, NP_001180528.1 and NP_001180546.1 respectively).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Pig, Bovine.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from an internal region of human SCP2 (NP_001007099.1, NP_002970.2, NP_001180528.1, NP_001180529.1, NP_001180546.1). Genename: SCP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SCP2

Target: SCP2 (Sterol Carrier Protein 2 (SCP2))

Alternative Name: SCP2 / SCPX (SCP2 Products)

Synonyms: NLTP antibody, NSL-TP antibody, SCP-2 antibody, SCP-CHI antibody, SCP-X antibody, SCPX antibody, AA409774 antibody, AA409893 antibody, C76618 antibody, C79031 antibody, ns-LTP antibody, NSLIPTR antibody, SCPx antibody, MGC77634 antibody, zgc:77634 antibody, SCP2 antibody, MGC108409 antibody, ATSCP2 antibody, MBD2.8 antibody, MBD2_8 antibody, STEROL CARRIER PROTEIN 2 antibody, PLTP antibody, zgc:101621 antibody, sterol carrier protein 2 antibody, sterol carrier protein 2, liver antibody, sterol carrier protein 2a antibody, sterol carrier protein 2 L homeolog antibody, phospholipid transfer protein homolog1 antibody, uncharacterized LOC101116445 antibody, sterol carrier protein 2b antibody, SCP2 antibody, Scp2 antibody, scp2a antibody, scp2.L antibody, scp2 antibody, CC1G_13192 antibody, plt1 antibody, LOC101116445 antibody, scp2b antibody

Background: This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms. The full-length nature of all transcript variants has not been determined. [provided by RefSeq]Synonyms: NSL-TP, Non-specific lipid-transfer protein, Propanoyl-CoA C-acyltransferase, SCP-2, SCP-X, SCP-chi, Sterol carrier protein 2, Sterol carrier protein X

Gene ID: 6342

NCBI Accession: NP_001007100

Pathways: C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process