SLC6A4 antibody (N-Term)

Catalog No. ABIN112474

This Mouse Monoclonal antibody specifically detects SLC6A4 in IHC (fro). It exhibits reactivity toward Rat and Mouse.

Quick Overview for SLC6A4 antibody (N-Term) (ABIN112474)

Target: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Reactivity: Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC6A4 antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 2D7-3

Product Details anti-SLC6A4 Antibody

Binding Specificity: AA 1-85, N-Term

Specificity: Reacts with the Serotonin Transporter (N-terminus).

Purification: Affinity Chromatography on Protein G

Immunogen: Rat serotonin transporter, N-terminus/GST fusion protein (aa 1-85)

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on frozen sections (0.5 - 1 μg/mL). Not suitable for western blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SLC6A4

Target: SLC6A4 (Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4))

Alternative Name: SLC6A4 / SERT

Background: SERT is a high affinity Na+, Cl- dependent transporter that clears serotonin from synaptic spaces to presynaptic neurons. It has been observed to migrate as 76 kDa from rat brain, due to postranslational modifications other bands are observed from different tissues.Synonyms: 5HT transporter, 5HTT, HTT, Sodium-dependent serotonin transporter, Solute carrier family 6 member 4

Gene ID: 6532

NCBI Accession: NP_001036

UniProt: P31645