Decorin antibody (AA 316-329)

Catalog No. ABIN113963

The Sheep Polyclonal anti-Decorin antibody is suitable to detect Decorin in samples from Human, Cow and Chicken. It has been validated for WB and EIA.

Quick Overview for Decorin antibody (AA 316-329) (ABIN113963)

Target: Decorin (DCN)

Reactivity: Human, Cow, Chicken

Host: Sheep

Clonality: Polyclonal

Conjugate: This Decorin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Decorin Antibody

Binding Specificity: AA 316-329

Sequence: C-V-Y-V-R-S-A-I-Q-L-G-N-Y-K

Specificity: This antibody detects Decorin.

Purification: Protein G chromatography

Immunogen: Synthetic peptide corresponding to the amino acids 316 - 329 of the native molecule conjugated to Keyhole Limpet Haemocyanin

Application Details

Application Notes: ELISA. Western blot (against bovine decorin, other batches have given a band at 90-100 kD,representative of full-length, glycanated decorin, this batch has not been fully evaluated inthis technique).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 12.2 mg/mL

Buffer: PBS, pH 7.2, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for Decorin

Target: Decorin (DCN)

Alternative Name: Decorin

Background: Decorin is a member of the small, leucine rich proteoglycan (SLRP) family along with biglycan. Found in the interterritorial region of cartilage, decorin interacts with collagen and other matrix proteins to regulate the cartilaginous matrix. It has been shown to interact with fibronectin, thrombospondin, C1q, epidermal growth factor receptor (EGFR), and TGF beta. It is believed that decorin also plays a role in the cell cycle of chondrocytes.Synonyms: Bone proteoglycan II, DCN, PG-S2, PG40, SLRR1B

Gene ID: 1634

NCBI Accession: NP_001911

UniProt: P07585

Pathways: Glycosaminoglycan Metabolic Process