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Cathepsin D (CTSD) antibody
| Antigen |
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| Synonyms |
CPSD, CLN10, MGC2311, CD, CatD, catD, fb93e11, fj17b09, wu:fb93e11, wu:fj17b09, CTSD, LOC398557, Cathd, LOC100136761, DKFZp469J0315 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Western Blotting (WB) (27), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), ELISA (15), Immunohistochemistry (IHC) (9), Enzyme Immunoassay (EIA) (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), Immunoprecipitation (IP) (4), Immunocytochemistry (ICC) (3), Flow Cytometry (FACS) (2), ELISA (Detection) (1), Immunoelectrophoresis (IEP) (1)
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| Catalog no. |
ABIN115287 |
| Quantity |
0,5 ml (Variants) |
| Price |
280.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: CTSD, CPSD
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Alternative name
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Cathepsin D
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Swiss-Prot
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P07339
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Immunogen
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Cathepsin D isolated from human liver.
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Description
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It stains fibroblasts and macrophages strongly but stains weakly with the myoepithelialcells of breast. It stains the sweat ducts and glands in the skin, islets cells and granules ofpancreatic acini.
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Specificity
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This antibody reacts with the zymogen as well as the activated form of cathepsin D. Cellular Localization: CytoplasmicSpecies: Human. Others not tested.
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Application Notes
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Immunohistochemistry on formalin-fixed paraffin embedded sections: diluted of 1: 75-1: 200 in an ABC method (30 minutes at room temperature)Recommended Positive Control: Breast carcinomaOther applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Buffer
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containing sodium azide as preservative.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Proteolysis / Ubiquitin, Extracellular Matrix, Proteases, Signaling
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Restrictions
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For Research Use only
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Publications
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Henry, McCarthy, Angus et al.: "Prognostic significance of the estrogen-regulated protein, cathepsin D, in breast cancer. An immunohistochemical study." in: Cancer, Vol. 65, Issue 2, pp. 265-71, 1990 (PubMed).
Horcajada, Garcia, Benito et al.: "[Specialized home care for infectious disease. Experience from 1995 to 2002]" in: Enfermedades infecciosas y microbiología clínica, Vol. 25, Issue 7, pp. 429-36, 2007 (PubMed).
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Alternatives for antigen "Cathepsin D (CTSD)", type "Antibodies"
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Hosts
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Rabbit (25), Mouse (12), Goat (1)
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Reactivities
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Human (37), Mouse (Murine) (6), Rat (Rattus) (5)
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Applications
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Western Blotting (WB) (27), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), ELISA (15), Immunohistochemistry (IHC) (9), Enzyme Immunoassay (EIA) (5), Immunohistochemistry (Frozen Sections) (IHC (fro)) (5), Immunoprecipitation (IP) (4), Immunocytochemistry (ICC) (3), Flow Cytometry (FACS) (2), ELISA (Detection) (1), Immunoelectrophoresis (IEP) (1)
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Epitopes
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Center (1)
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