Cathepsin D antibody (C-Term)

Catalog No. ABIN2776841

There is 1 publication for this product available. The Rabbit Polyclonal anti-Cathepsin D antibody is suitable to detect Cathepsin D in samples from Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig, Saccharomyces cerevisiae and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for Cathepsin D antibody (C-Term) (ABIN2776841)

Target: Cathepsin D (CTSD)

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cathepsin D Antibody

Binding Specificity: C-Term

Purpose: Ctsd Antibody - C-terminal region

Sequence: KTICLSGFMG MDIPPPSGPL WILGDVFIGS YYTVFDRDNN RVGFANAVVL

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 93%, Yeast: 92%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against Ctsd. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41481-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-Cathepsin D antibody (ABIN2776841)

Gambarte Tudela, Capmany, Romao, Quintero, Miserey-Lenkei, Raposo, Goud, Damiani: "The late endocytic Rab39a GTPase regulates the interaction between multivesicular bodies and chlamydial inclusions." in: Journal of cell science, Vol. 128, Issue 16, pp. 3068-81, (2015) (PubMed).

Target Details for Cathepsin D

Target: Cathepsin D (CTSD)

Alternative Name: Ctsd

Background:

Background Information: Ctsd is an acid protease active in intracellular protein breakdown.

Gene Name: Cathepsin D

Alternative Symbols: CD, Cat, CatD

Protein Name: Cathepsin D

Molecular Weight: 45kDa

Gene ID: 13033

NCBI Accession: NP_034113

UniProt: P18242

Pathways: Peptide Hormone Metabolism