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Details for Product No. ABIN118519

Interleukin 5 (IL5) antibody

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Antigen
Synonyms EDF, TRF, IL-5, Il-5, IL5
Reactivity
»Alternatives Guinea Pig, Human, Mouse (Murine)
Host
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 4 references available
Catalog no. ABIN118519
Quantity 0.5 mg
Price
720.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Purified natural murine IL-5.
Clone TRFK5
Isotype IgG1
Specificity This antibody is specific for Interleukin 5 (IL-5). Clone TRFK5 may be used to neutralise IL-5 bioactivity in a functional assay (1,2).
Purification Affinity chromatography on Protein G
Alternative Name Interleukin-5 / IL5
Background IL-5 is a T cell derived haematopoietic growth factor, which stimulates eosinophil differentiation and activation.
Alternate names: B-cell differentiation factor I, Eosinophil differentiation factor, IL-5, T-cell replacing factor, TRF
Gene ID 3567
NCBI Accession NP_000870.1
UniProt P05113
Application Notes Flow Cytometry: Membrane permeabilisation is required for this application. ELISA: This antibody may be used in combination with clone TRFK4 (ABIN181863) in ELISA and ELISPOT assays. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 0.09% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Schumacher, OGarra, Shrader et al.: "The characterization of four monoclonal antibodies specific for mouse IL-5 and development of mouse and human IL-5 enzyme-linked immunosorbent." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 141, Issue 5, pp. 1576-81, 1988 (PubMed).

Abrams, Roncarolo, Yssel et al.: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, 1992 (PubMed).

Betz, Fox: "Regulation and development of cytochrome c-specific IL-4-producing T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 145, Issue 4, pp. 1046-52, 1990 (PubMed).

Akdis, Akdis, Blesken et al.: "Epitope-specific T cell tolerance to phospholipase A2 in bee venom immunotherapy and recovery by IL-2 and IL-15 in vitro." in: The Journal of clinical investigation, Vol. 98, Issue 7, pp. 1676-83, 1996 (PubMed).

Alternatives for antigen "Interleukin 5 (IL5)", type "Antibodies"
Hosts (67), (56), (5), (2)
Reactivities (89), (68), (18), (2), (1), (1)
Applications (92), (75), (25), (11), (10), (7), (7), (7), (6), (4), (3), (2), (2), (1), (1), (1)
Conjugates (27), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (5), (2), (2), (1), (1), (1), (1), (1), (1)
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