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ICAM1 antibody

ICAM1 Reactivity: Human, Dog WB, FACS, IP, IHC (fro) Host: Mouse Monoclonal 84H10 unconjugated
Catalog No. ABIN118732
  • Target See all ICAM1 Antibodies
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Reactivity
    • 208
    • 80
    • 38
    • 7
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    Human, Dog
    Host
    • 120
    • 107
    • 27
    • 4
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 139
    • 119
    • 1
    Monoclonal
    Conjugate
    • 120
    • 26
    • 23
    • 18
    • 9
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ICAM1 antibody is un-conjugated
    Application
    • 165
    • 149
    • 62
    • 61
    • 44
    • 40
    • 35
    • 34
    • 28
    • 28
    • 25
    • 20
    • 12
    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Affinity Chromatography on Protein A
    Immunogen
    K562 cell line. Spleen cells from immunised BALB/c mice were fused with cells of the MOPC 315 mouse myeloma cell line.
    Clone
    84H10
    Isotype
    IgG1
    Top Product
    Discover our top product ICAM1 Primary Antibody
  • Application Notes
    Flow Cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 10^6 cells in 100 μL. Immunohistochemistry on Frozen Sections (1/20-1/50). Immunoprecipitation: 5 μg/10e7 cells. Removal of sodium azide is recommended prior to use in functional assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))
    Alternative Name
    CD54 / ICAM1 (ICAM1 Products)
    Synonyms
    BB2 antibody, CD54 antibody, P3.58 antibody, Icam-1 antibody, Ly-47 antibody, MALA-2 antibody, ICAM antibody, ICAM-1 antibody, ICAM1 antibody, intercellular adhesion molecule 1 antibody, intercellular adhesion molecule-1 antibody, ICAM1 antibody, Icam1 antibody, ICAM-1 antibody
    Target Type
    Viral Protein
    Background
    ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.Synonyms: ICAM-1, Intercellular adhesion molecule 1, Major Group Rhinovirus Receptor
    Gene ID
    9606
    UniProt
    P05362
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling
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