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CD151 Molecule (Raph Blood Group) (CD151) antibody (FITC)

Details for Product No. ABIN118881, Supplier: Log in to see
Antigen
  • CD151
  • MGC83668
  • gp27
  • mer2
  • raph
  • sfa1
  • peta-3
  • tspan24
  • PETA-3
  • SFA-1
  • Tspan24
  • GP27
  • MER2
  • RAPH
  • SFA1
  • TSPAN24
Reactivity
Human
97
21
21
6
2
1
Host
Mouse
54
52
Clonality (Clone)
Monoclonal ()
Conjugate
FITC
14
11
5
3
3
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
51
47
40
16
14
11
10
8
5
3
3
3
Supplier
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Immunogen Spleen cells from immunised BALB/c mice were fused with cells of the X63.Ag8.653 mouse myeloma cell line.
Clone 11G5a
Isotype IgG1
Specificity This antibody recognises the CD151 cell surface antigen, also known as PETA-3.
Purification Affinity chromatography on Protein G.
Alternative Name CD151 / TSPAN24 (CD151 Antibody Abstract)
Background CD151 is expressed by epithelial cells, endothelial cells, platelets, megakaryocytes, monocytes and in the renal glomeruli and proximal and distal tubules. CD151 is not expressed by lymphocytes or granulocytes. More recently CD151 has also been shown to be expressed by erythrocytes, and to carry the MER2 blood group antigen. It should be noted that CD151 is very closely associated with the alpha3 beta1 integrin in cells and co-immunoprecipitation may occur even in quite stringent conditions.Synonyms: GP27, Membrane glycoprotein SFA-1, PETA-3, PETA3, Platelet-endothelial tetraspan antigen 3, SFA-1, SFA1, Tetraspanin-24
Gene ID 977
NCBI Accession NP_001034579
UniProt P48509
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways
Application Notes Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.1 mg/mL
Handling Advice Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Karamatic Crew, Burton, Kagan et al.: "CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skin." in: Blood, Vol. 104, Issue 8, pp. 2217-23, 2004 (PubMed).

Yauch, Berditchevski, Harler et al.: "Highly stoichiometric, stable, and specific association of integrin alpha3beta1 with CD151 provides a major link to phosphatidylinositol 4-kinase, and may regulate cell migration." in: Molecular biology of the cell, Vol. 9, Issue 10, pp. 2751-65, 1998 (PubMed).