FSH antibody

Catalog No. ABIN118955

Product Details anti-FSH Antibody

Target: FSH (Follicle-Stimulating Hormone (FSH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FSH antibody is un-conjugated

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: The antibody is directed against the beta 2 epitope of the beta subunit of FSH. Shows strong reactions with FSH and beta-FSH, but no cross-reactivity with TSH, LH, HCG, alph-HCG or alpha-FSH. The recognition site is located near the alpha 1 binding site on the hFSH molecule. It is not compatible with other anti-hFSH-beta antibodies.

Purification: Protein A affinity chromatography

Immunogen: Human FSH

Clone: INN-hFSH-60

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on frozen and paraffin embedded sections (recommended positive control: Pituitary Gland). ELISA (in combination with antibody ABIN119035 it can be used to detect holo-hFSH bound to a solid phase).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FSH

Target: FSH (Follicle-Stimulating Hormone (FSH))

Alternative Name: Follicle-Stimulating Hormone / FSH (FSH Products)

Synonyms: FSH antibody, Fshbeta antibody, follicle stimulating hormone beta antibody, Plasma FSH concentration antibody, Fshb antibody, FSH antibody

Background: Follicle stimulating hormone enables ovarian folliculogenesis to the antral follicle stage and is essential for Sertoli cell proliferation and maintenance of sperm quality in the testis. Members of the pituitary glycoprotein hormone family, of which FSH is one consist of a shared alpha chain and a beta chain encoded by a separate gene. The FSH beta gene encodes the beta subunit of follicle stimulating hormone.Synonyms: FSH beta, FSHB, Follitropin beta chain

Gene ID: 2488

NCBI Accession: NP_000501

UniProt: P01225

Pathways: Peptide Hormone Metabolism, Chromatin Binding