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Glial Cell Line Derived Neurotrophic Factor Family Receptor alpha 1 (GFRA1) (C-Term) antibody

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Antigen
  • AU042498
Epitope
C-Term
2
2
1
1
Reactivity
Human
9
5
5
Host
Rabbit
7
2
Clonality
Polyclonal
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
8
3
1
1
1
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Immunogen Peptide from C terminus of human GDNFR alpha
Purification Ion Exchange Chromatography
Alternative Name GFRA1 / GDNFR-alpha (GFRA1 Antibody Abstract)
Background GDNFR alpha has more recently been designated GFR alpha -1.Synonyms: GDNF family receptor alpha-1, GDNF receptor alpha, GDNFRA, GFR-alpha-1, RET ligand 1, RETL1, TGF-beta-related neurotrophic factor receptor 1, TRNR1
UniProt P56159
Application Notes Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Background publications Treanor, Goodman, de Sauvage, Stone, Poulsen, Beck, Gray, Armanini, Pollock, Hefti, Phillips, Goddard, Moore, Buj-Bello, Davies, Asai, Takahashi, Vandlen, Henderson, Rosenthal: "Characterization of a multicomponent receptor for GDNF." in: Nature, Vol. 382, Issue 6586, pp. 80-3, 1996 (PubMed).

Jing, Wen, Yu, Holst, Luo, Fang, Tamir, Antonio, Hu, Cupples, Louis, Hu, Altrock, Fox: "GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNF." in: Cell, Vol. 85, Issue 7, pp. 1113-24, 1996 (PubMed).