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TNFRSF25 antibody (Tumor Necrosis Factor Receptor Superfamily, Member 25) (N-Term)

Details for Product anti-TNFRSF25 Antibody No. ABIN121506, Supplier: Log in to see
Antigen
  • APO-3
  • DDR3
  • DR3
  • LARD
  • Tnfrsf12
  • TNFRSF12
  • TNFRSF25
  • TR3
  • TRAMP
  • Wsl
  • WSL-1
  • WSL-LR
Alternatives
anti-Human TNFRSF25 antibody for Western Blotting
Epitope
N-Term
17
15
15
13
13
10
10
10
5
4
3
3
3
2
2
2
1
1
Reactivity
Human
171
61
28
2
Host
Rabbit
144
33
4
1
Clonality
Polyclonal
Conjugate
This TNFRSF25 antibody is un-conjugated
11
10
4
4
2
2
2
2
2
2
2
2
2
2
2
Application
Western Blotting (WB)
122
60
23
22
22
18
10
6
5
2
2
2
1
1
1
Supplier
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Immunogen Peptide sequence from amino terminus of human DR3 AA Sequence: QGGTRSPRCDCAGDFH
Purification Ion exchange chromatography
Alternative Name TNFRSF25 / DR3 / TRAMP (TNFRSF25 Antibody Abstract)
Background DR3 is a cell surface receptor with a death domain, with functional similarities to TNFR1 and Fas (CD95). The ligand for DR3 has very recently been identified and has been termed Apo-3L. DR3 itself has also been called Wsl-1, Apo-3, TRAMP and LARD, and functionally induces apoptosis and NF-KB activation.Synonyms: AIR, APO3, Apo-3, Apoptosis-inducing receptor AIR, Apoptosis-mediating receptor DR3, Apoptosis-mediating receptor TRAMP, DDR3, Death receptor 3, LARD, Lymphocyte-associated receptor of death, Protein WSL, Protein WSL-1, TNFRSF12, Tumor necrosis factor receptor superfamily member 25, WSL, WSL1
UniProt Q93038
Pathways Apoptosis
Application Notes Western blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Background publications Marsters, Sheridan, Pitti, Brush, Goddard, Ashkenazi: "Identification of a ligand for the death-domain-containing receptor Apo3." in: Current biology : CB, Vol. 8, Issue 9, pp. 525-8, 1998 (PubMed).

Chinnaiyan, ORourke, Yu, Lyons, Garg, Duan, Xing, Gentz, Ni, Dixit: "Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95." in: Science (New York, N.Y.), Vol. 274, Issue 5289, pp. 990-2, 1996 (PubMed).