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Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10) (C-Term) antibody

Antigen

Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)
Synonyms TL2, APO2L, CD253, TRAIL, Apo-2L, Ly81, Trail, APO-2L, AI448571, A330042I21Rik, TRAIL-LIKE, TNFSF10, tl2, apo2l, cd253, trail, apo-2l, trail1, xtrail1
Binding Site
Alternatives

C-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
2 references available
Catalog no. ABIN121515
Quantity 0.1 mg  (0.5 mg/ml)  (Variants)
Price 330.00 $   Plus shipping costs $45.00
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Additional Information
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Alternative name CD253 / TRAIL
UniProt P50591
Immunogen Peptide from C-terminus of human CD253 (TRAIL)
Cross-Reactivity Human
Description TRAIL also known as CD253, is a type II membrane protein expressed in a variety of tissues. Receptors for TRAIL have recently been identified and termed DR4 and DR5. Alternate Names: TNFSF10, APO2L, TRAIL, TNF-related apoptosis-inducing ligand, Protein TRAIL, Apo-2 ligand, Apo- 2L, CD253, , Tumor necrosis factor ligand superfamily member 10.
Specificity This antibody recognises the 32kD apoptosis related protein designated TRAIL (TNF-related apoptosis-inducing ligand).

Application Details
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Application Notes Western Blot: 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 0.5 mg/ml
Purification Purified
Buffer PBS containing 0.02% Sodium Azide
Storage Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Research Area Cancer, Apoptosis/Necrosis
Restrictions For Research Use only

Publications
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Pitti, Marsters, Ruppert et al.: "Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12687-90, 1996 (PubMed).

Wiley, Schooley, Smolak et al.: "Identification and characterization of a new member of the TNF family that induces apoptosis." in: Immunity, Vol. 3, Issue 6, pp. 673-82, 1996 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10)", type "Antibodies"
Hosts Rabbit (79), Mouse (37), Rat (11), Chicken (2), Goat (1)
Reactivities Human (120), Mouse (Murine) (37), Rat (Rattus) (23), Pig (Porcine) (2), Cow (Bovine) (1), Dog (Canine) (1), Rabbit (1)
Applications Western Blotting (WB) (79), ELISA (53), Flow Cytometry (FACS) (33), Immunofluorescence (IF) (22), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), Immunohistochemistry (IHC) (12), Functional Studies (Func) (10), Immunoprecipitation (IP) (10), Neutralization (Neut) (4), Immunohistochemistry (Fixed) (IHC (fx)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Blocking Antibody (Inhibition) (1), Blocking Antibody (Inhibition) (1), ELISA (Capture) (1), ELISA (Detection) (1), Enzyme Immunoassay (EIA) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Biotin (15), PE (8), FITC (2), HRP (2), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (10), AA 95-281 (3), AA 17-35 (2), N-Term (2), AA 139-281 (1), AA 207-220 (1), AA 261-277 (1), Center (1), Center, Asn109 (1), Internal Region (1)