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TNFSF10 antibody (Tumor Necrosis Factor (Ligand) Superfamily, Member 10) (C-Term)

Details for Product anti-TNFSF10 Antibody No. ABIN121515, Supplier: Log in to see
Antigen
  • TRAIL
  • tl2
  • apo2l
  • cd253
  • trail
  • apo-2l
  • trail1
  • xtrail1
  • APO2L
  • Apo-2L
  • CD253
  • TL2
  • A330042I21Rik
  • AI448571
  • APO-2L
  • Ly81
  • Trail
Alternatives
anti-Human TNFSF10 antibody for Functional Studies
Epitope
C-Term
27
22
13
7
6
6
5
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human
263
65
26
2
2
1
Host
Rabbit
184
100
24
2
1
Clonality
Polyclonal
Conjugate
This TNFSF10 antibody is un-conjugated
33
17
13
9
6
3
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
198
119
83
47
24
22
16
14
13
11
10
8
5
2
2
2
2
2
1
1
1
1
Supplier
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Immunogen Peptide from C-terminus of human CD253 (TRAIL)
Isotype IgG
Purification Ion Exchange Chromatography
Alternative Name CD253 / TRAIL (TNFSF10 Antibody Abstract)
Background TRAIL also known as CD253, is a type II membrane protein expressed in a variety of tissues. Receptors for TRAIL have recently been identified and termed DR4 and DR5.Synonyms: APO2L, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, TNFSF10, Tumor necrosis factor ligand superfamily member 10
UniProt P50591
Research Area Cancer, Apoptosis/Necrosis
Pathways Apoptosis
Application Notes Western Blot: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Background publications Wiley, Schooley, Smolak et al.: "Identification and characterization of a new member of the TNF family that induces apoptosis." in: Immunity, Vol. 3, Issue 6, pp. 673-82, 1996 (PubMed).

Pitti, Marsters, Ruppert et al.: "Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family." in: The Journal of biological chemistry, Vol. 271, Issue 22, pp. 12687-90, 1996 (PubMed).