GPRC6A antibody (N-Term)

Catalog No. ABIN122201

There is 1 publication for this product available. The Rabbit Polyclonal anti-GPRC6A antibody is suitable to detect GPRC6A in samples from Human and Monkey. It has been validated for IHC (p).

Quick Overview for GPRC6A antibody (N-Term) (ABIN122201)

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPRC6A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GPRC6A Antibody

Binding Specificity: N-Term

Specificity: Reacts with G Protein-Coupled Receptor GPRC6A (family: GPCR, subfamily: Amino Acid Receptor)

Cross-Reactivity (Details): Species reactivity (expected):Monkey, Dog, Horse, Pig, RabbitSpecies reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 11 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

References for anti-GPRC6A antibody (ABIN122201)

Haid, Jordan-Biegger, Widmayer, Breer: "Receptors responsive to protein breakdown products in g-cells and d-cells of mouse, swine and human." in: Frontiers in physiology, Vol. 3, pp. 65, (2012) (PubMed).

Target Details for GPRC6A

Target: GPRC6A (G Protein-Coupled Receptor, Family C, Group 6, Member A (GPRC6A))

Background: GPRC6A has been shown to bind to L-alpha-amino acids. Recently GPRC6A has been suggested to be a calcium-sensing receptor. Ligand: L-alpha-amino acids, including L-Arg, L-Lys and L-ornithineSynonyms: G-protein coupled receptor family C group 6 member A

Gene ID: 222545

UniProt: Q5T6X5