gpcr antibody, GPCR antibody, bA86F4.3 antibody, G protein-coupled receptor class C group 6 member A antibody, G protein-coupled receptor, family C, group 6, member A antibody, G protein-coupled receptor, class C, group 6, member A antibody, GPRC6A antibody, gprc6a antibody, Gprc6a antibody
Background
Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca2+ and Mg2+. Activated by extracellular calcium and osteocalcin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids.