Immunohistochemistry with formalin fixed paraffin embedded tissues: 6 - 15 μg/mL. Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS, pH 7.7 containing 0.09 % Sodium Azide as preservative.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer. Avoid repeated freezing and thawing. Shelf Life: one year from despatch.
Expiry Date
12 months
Target
PTGER2
(Prostaglandin E Receptor 2 (Subtype EP2), 53kDa (PTGER2))
Prostaglandin E Receptor EP2 is a member of the Prostanoid Receptor subfamily. Along with several other receptor subtypes (EP1, EP3, and EP4), it mediates the diverse biological effects of Prostaglandin E2 (PGE2). PGE2 has been implicated in numerous processes, including immune response modulation, male erectile function, induction of labor, cervical cancer, control of blood pressure, asthma, and more recently, Alzheimer's Disease. Prostaglandin E Receptor EP2 expression has been documented in eye, ovary, uterus, and vessel. ESTs have been isolated from bone marrow and heart/melanocyte/uterus libraries.Synonyms: EP2, PGE receptor EP2, PGE2 receptor EP2 subtype, Prostaglandin E receptor 2, Prostaglandin E2 receptor EP2, Prostanoid EP2 receptor