GPR124 antibody

Catalog No. ABIN122437

Product Details anti-GPR124 Antibody

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPR124 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with Tumor Endothelial Marker 5 (family: GPCR, subfamily: Orphan-U)

Purification: Peptide immunogen affinity column

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 4 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.7, containing 0.01 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for GPR124

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Alternative Name: GPR124 / TEM5 (GPR124 Products)

Synonyms: TEM5 antibody, 8430414O08Rik antibody, 9530074E10Rik antibody, Tem5 antibody, mKIAA1531 antibody, MGC69043 antibody, si:dkey-208c22.2 antibody, GPR124 antibody, adhesion G protein-coupled receptor A2 antibody, adhesion G protein-coupled receptor A2 L homeolog antibody, G-protein coupled receptor 124 antibody, ADGRA2 antibody, Adgra2 antibody, adgra2.L antibody, adgra2 antibody, LOC616111 antibody

Background: Tumor endothelial marker 5 is an Orphan-U GPCR with an unknown ligand. Tumor Endothelial Marker 5, like GPR125, has a leucine rich repeat (LRR), an immunoglobulin (Ig) domain, and a hormone-binding domain (HBD). The Ig domain shows similarities to motilin and titin, while the LRR domain shows similarities to LRIG1 and SLIT1-2. TEM5 expression has been documented in endothelial cells of tumors, including colon, brain, liver. Expression is restricted largely to endothelial cells.Synonyms: G-protein coupled receptor 124, KIAA1531, Tumor endothelial marker 5

Gene ID: 25960

UniProt: Q96PE1