AVPR1B antibody

Catalog No. ABIN122568

The Rabbit Polyclonal anti-AVPR1B antibody (ABIN122568) specifically detects AVPR1B in IHC (p). The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for AVPR1B antibody (ABIN122568)

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR1B antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AVPR1B Antibody

Specificity: Reacts with Vasopressin V1B Receptor (Family: GPCR, subfamily: Vasopressin/oxytocin)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 4 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for AVPR1B

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Alternative Name: Vasopressin V1b Receptor (V1bR)

Background: The vasopressin V1B receptor is a member of the Vasopressin/Oxytocin Family subfamily. The V1B receptor is expressed specifically in pituitary corticotropes and mediates the stimulatory effect of vasopressin on adrenocorticotropic hormone (ACTH) release. Vasopressin V1B receptor expression has been documented in the pituitary, pituitary tumors, pheochromocytoma, breast cancer, and small-cell lung carcinomas.Synonyms: AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Avpr1b, Vasopressin V3 receptor

Gene ID: 553

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones