Annexin VIII antibody

Catalog No. ABIN127268

The Rabbit Polyclonal anti-Annexin VIII antibody is suitable to detect Annexin VIII in samples from Human. It has been validated for WB.

Quick Overview for Annexin VIII antibody (ABIN127268)

Target: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin VIII antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Annexin VIII Antibody

Specificity: The antibody detects 36 kDa annexin VIII of Human origin. The ~28-30 kDa cleavage fragments can also be detected in Jurkat cell lysate. Blocking peptide is available separately (AP00292CP-N).

Purification: Protein A Affinity Chromatography

Immunogen: Synthetic peptide surrounding amino acid 316 of Human Annexin VIII.

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2 containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for Annexin VIII

Target: Annexin VIII (ANXA8) (Annexin A8 (ANXA8))

Alternative Name: Annexin A8 / ANXA8

Background: The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner. Annexin family members have been implicated as regulators of diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate its role in hematopoietic cell differentiation.Synonyms: ANX8, Annexin VIII, Annexin-8, VAC-beta, Vascular anticoagulant-beta

Gene ID: 244

NCBI Accession: NP_001035173

UniProt: P13928