BCLAF1 antibody

Catalog No. ABIN127331

Product Details anti-BCLAF1 Antibody

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCLAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificity: The antibody recognizes the BTF.

Purification: Affinity Purified

Immunogen: Synthetic peptide of human BTF

Application Details

Application Notes: Western Blot: 1: 500-1: 2000. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 30 % glycerol, 1 % BSA and 0.02 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for BCLAF1

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Alternative Name: BCLAF1 / BTF (BCLAF1 Products)

Synonyms: Aa2-041 antibody, Fam54a antibody, Mtfr2 antibody, 2610102K23Rik antibody, 2700025J07Rik antibody, 2810454G14Rik antibody, 5730534O06Rik antibody, AI450190 antibody, AW556225 antibody, Btf antibody, mKIAA0164 antibody, btf antibody, bk211l9.1 antibody, BCLAF1 antibody, DKFZp468F0113 antibody, BTF antibody, bK211L9.1 antibody, BCL2-associated transcription factor 1 antibody, BCL2 associated transcription factor 1 antibody, mitochondrial fission regulator 2 antibody, Bclaf1 antibody, BCLAF1 antibody, bclaf1 antibody, MTFR2 antibody

Background: BTF is a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. BTF localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this protein.Synonyms: Aa2-041, Bcl-2-associated transcription factor 1, KIAA0164

Gene ID: 9774

NCBI Accession: NP_001070908

UniProt: Q9NYF8

Pathways: Positive Regulation of Response to DNA Damage Stimulus