CD4 antibody
Quick Overview for CD4 antibody (ABIN135105)
Target
See all CD4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
-
-
Purpose
- Rat Anti-Mouse CD4-LE/AF
-
Specificity
- Mouse CD4, Mr 55 kDa
-
Characteristics
- Low Endotoxin/Azide Free Anti-Mouse CD4 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, depletion, separation, and blocking assays.
-
Endotoxin Level
- Low Endotoxin
-
Immunogen
- Mouse CTL clone V4
-
Isotype
- IgG2b
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- Phosphate buffered saline, pH 7.4
-
Preservative
- Azide free
-
Handling Advice
- Each reagent is stable for the period shown on the bottle label if stored as directed.
-
Storage
- 4 °C
-
Storage Comment
- 2-8°C
-
-
- CD4
-
Alternative Name
- CD4
-
Background
- CD4/L3T4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells.
-
Gene ID
- 12504
-
UniProt
- P06332
-
Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
-