You are viewing an incomplete version of our website. Please click to reload the website as full version.

CD11b antibody (Integrin alpha M)

Details for Product anti-ITGAM Antibody No. ABIN135128, Supplier: Log in to see
Antigen
  • CD11b/CD18
  • CR3
  • CR3A
  • Cd11b
  • F730045J24Rik
  • Ly-40
  • MAC1
  • Mac-1
  • Mac-1a
  • CD11B
  • MAC-1
  • MAC1A
  • MO1A
  • SLEB6
  • C3bi
Alternatives
anti-Mouse (Murine) CD11b antibody for Immunohistochemistry
Reactivity
Mouse (Murine)
538
429
133
44
20
17
17
17
17
11
10
9
5
4
3
2
2
1
Host
Rat
435
386
105
16
4
2
Clonality (Clone)
Monoclonal ()
Conjugate
This CD11b antibody is un-conjugated
159
117
84
49
18
17
12
11
11
8
7
7
7
7
6
6
5
4
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunoprecipitation (IP)
741
203
177
123
110
81
77
57
47
32
19
15
11
7
6
5
4
3
3
3
3
3
2
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Immunogen Peritoneal macrophages from C57 B1/6 x DBA/2 F1 hybrid mice1
Clone 3A33
Isotype IgG2a
Characteristics The antibody detects: M subunit (Mr 170 kDa) of the CD11b/CD18 heterodimer
Purification Purified
Alternative Name CD11b/Mac-1a (ITGAM Antibody Abstract)
Background CD11b (integrin M subunit) combines with CD18 (integrin 2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils.
Pathways Apoptosis
Application Notes Working Dilution:
FACS: 1 µg/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Sample Volume 1 mL
Restrictions For Research Use only
Buffer Product is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0.
Preservative Azide free
Handling Advice Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Background publications Springer: "Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm." in: Cell, Vol. 76, Issue 2, pp. 301-14, 1994 (PubMed).