Integrin beta 3 antibody

Catalog No. ABIN135712

Product Details anti-Integrin beta 3 Antibody

Target: Integrin beta 3 (ITGB3)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 3 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Specificity: Human CD61, Mr 110 kDa

Characteristics: Mouse Anti-Human CD61-UNLB

Purification: Purified

Immunogen: Human platelet plasma membrane

Clone: PM6-13

Isotype: IgG1

Application Details

Application Notes:

• Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature , WB-NR - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature , ELISA - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and PE conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Sample Volume: 1 mL

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: 0.1 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

Preservative: Without preservative

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: CD61 (ITGB3 Products)

Background: CD61 is the integrin 3 subunit, a 105 kDa transmembrane glycoprotein expressed on platelets, megakaryocytes, and endothelial cells. Integrin 3 associates with gpIIb (CD41) to form the CD41/CD61 complex that mediates platelet adhesion and aggregation. CD61 also associates with CD51 to form the V3 vitronectin receptor.

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex