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CD8 antibody (CD8a Molecule) (PE)

Details for Product anti-CD8A Antibody No. ABIN135737, Supplier: Log in to see
Antigen
  • cd8
  • LOC100136450
  • BB154331
  • Ly-2
  • Ly-35
  • Ly-B
  • Lyt-2
  • zgc:136643
  • CD8
  • Leu2
  • MAL
  • p32
  • RHACD8-4
  • CD8 antigen, alpha chain
  • CD8 antigen, alpha polypeptide
  • CD8 alpha
  • T-cell surface glycoprotein CD8 alpha chain-like
  • CD8a molecule
  • Cd8a
  • cd8
  • LOC100136450
  • LOC100387674
  • cd8a
  • CD8A
Alternatives
anti-Human CD8 antibody for Immunohistochemistry (Frozen Sections)
Reactivity
Human
1084
551
167
77
50
41
25
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17
13
13
13
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12
12
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10
3
3
2
2
2
1
1
1
1
Host
Mouse
1318
526
219
1
Clonality (Clone)
Monoclonal ()
Conjugate
This CD8 antibody is conjugated to PE
271
223
143
82
59
47
44
40
35
32
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27
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26
22
22
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3
3
2
2
2
2
1
1
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1
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1
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1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC)
1671
478
455
323
272
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258
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225
39
32
25
25
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23
18
14
11
10
7
7
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4
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Options
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Clone RFT-8
Isotype IgG1
Characteristics The antibody detects: Human CD8
Purification Ion exchange column
Alternative Name CD8 (CD8A Antibody Abstract)
Background CD8 is a 32 kDa transmembrane glycoprotein expressed as either a CD8 homodimer or CD8 heterodimer. It is expressed on the cytotoxic/suppressor subpopulation of peripheral T cells. CD8 functions primarily as a coreceptor with MHC Class I-restricted TCR's in antigen recognition.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Pathways TCR Signaling
Application Notes Working Dilution:
FACS: 10 µL/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions For Research Use only
Buffer Product is supplied as100 tests in 1.0 mL of PBS / NaN3 and a stabilizing agent.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Do not freeze!
Protect conjugated products from light.

Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
Background publications Zamoyska: "The CD8 coreceptor revisited: one chain good, two chains better." in: Immunity, Vol. 1, Issue 4, pp. 243-6, 1995 (PubMed).