anti-CD11b antibody (Integrin alpha M)

Details for Product anti-ITGAM Antibody No. ABIN135738
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Synonyms CD11b/CD18, CR3, CR3A, Cd11b, F730045J24Rik, Ly-40, MAC1, Mac-1, Mac-1a, CD11B, MAC-1, MAC1A, MO1A, SLEB6, C3bi
(417), (353), (91), (25), (19), (13), (7), (6), (3), (2), (1), (1), (1)
(354), (330), (74), (17), (3)
Clonality (Clone)
Monoclonal ()
This CD11b antibody is conjugated to PE
(135), (99), (79), (38), (14), (8), (8), (8), (7), (6), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
Flow Cytometry (FACS), Immunohistochemistry (IHC)
(618), (182), (170), (118), (98), (65), (61), (37), (36), (25), (17), (9), (7), (6), (3), (3), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 100 tests
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Clone ICRF44
Isotype IgG1
Characteristics The antibody detects: Human CD11b/Mac-1
Alternative Name CD11b/Mac-1a (ITGAM Antibody Abstract)
Background CD11b is the 165 kDa M chain which combines with the CD18 2 integrin subunit to form the Mac-1 heterodimer. It is expressed on activated lymphocytes, monocytes, granulocytes and a subset of NK cells. CD11b/Mac-1 functions in cell-cell and cell-substrate interactions and is a ligand for C3bi, CD50 (ICAM-3), CD54 (ICAM-1) and CD102 (ICAM-2).
Application Notes Working Dilution:
FACS: 2 µL/10^6 cells
Representative data are included in this product insert.

Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Blocking Studies

Restrictions For Research Use only
Buffer Product is supplied as 100 tests in 1.0 mL of PBS / NaN3 and a stabilizing agent.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Do not freeze!
Protect conjugated products from light.

Each reagent is stable for the period shown on the bottle label if stored as directed.
Storage 4 °C
General Lee, Bankston, Arnaout et al.: "Two conformations of the integrin A-domain (I-domain): a pathway for activation?" in: Structure (London, England : 1993), Vol. 3, Issue 12, pp. 1333-40, 1996 (PubMed).

Springer: "Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm." in: Cell, Vol. 76, Issue 2, pp. 301-14, 1994 (PubMed).

Validation Images
Catalog No. ABIN135738
283.80 $
Plus shipping costs $45.00
100 tests
283.80 $

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